Publications
Selected publications
A curated selection of landmark and recent papers relevant to the lab's focus on p53 dynamics, DNA damage responses and signalling crosstalk.
Molecular Systems Biology
Stimulus-dependent dynamics of p53 in single cells
Science (Purvis et al.)
p53 dynamics control cell fate
Molecular Cell
Global inhibition with specific activation: how p53 and MYC redistribute the transcriptome in the DNA double-strand break response
Journal of Cell Biology
Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing
Communications Biology
Two‑Stage Regulation of MYC Expression in Primary Single Cells
Cell Reports
Rucaparib alters p53 oscillations in single cells to enhance DNA-double-strand-break-induced cell cycle arrest
Molecular Systems Biology
Coordination of MAPK and p53 dynamics in the cellular responses to DNA damage and oxidative stress
Molecular Cell